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An optimised method for bacterial nucleic acid extraction from positive blood culture broths for whole genome sequencing, resistance phenotype prediction and downstream molecular applications

2022-07-02

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> A prerequisite to rapid molecular detection of pathogens causing bloodstream infections is an efficient, cost effective and robust DNA extraction solution. We describe methods for microbial DNA extraction direct from positive blood culture broths, suitable for metagenomic sequencing and the application of machine-learning based tools to predict antimicrobial susceptibility....

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Literature Corpus work
45bd9866-315b-55e2-ade5-d4c28e5ccf3f
DOI
10.1101/2022.06.30.497578
Open publication

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An optimised method for bacterial nucleic acid extraction from positive blood culture broths for whole genome sequencing, resistance phenotype prediction and downstream molecular applicationsDOI 10.1101/2022.06.30.497578
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