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Rapid and modular workflows for same-day sequencing-based detection of bloodstream infections and antimicrobial resistance determinants

2024-10-09

Abstract excerpt

<h4>Background</h4> Bloodstream infections (BSI) are a major global health concern, and existing diagnostic methods are too slow to guide targeted antibiotic therapy for critically ill patients, risking poor clinical outcomes. Rapid metagenomic-sequencing (mNGS) can facilitate swift pathogen and antimicrobial resistance (AMR) detection, but identification is challenged by significant host versus bacterial DNA in b...

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Literature Corpus work
3a1855c5-393c-50ee-904d-63c513e36741
DOI
10.1101/2024.10.09.24315014
Open publication

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Rapid and modular workflows for same-day sequencing-based detection of bloodstream infections and antimicrobial resistance determinantsDOI 10.1101/2024.10.09.24315014
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