Article

From culture to clarity in four hours: accelerating clinical management of bloodstream infections using metagenomics

2026-07-20

Abstract excerpt

<h4>Background</h4> Metagenomic next-generation sequencing (mNGS) has the potential to transform clinical diagnostics for bloodstream infections (BSIs). However, its clinical utility is currently limited by several challenges, including the extraction of DNA from blood cultures. Our aim was to develop, evaluate, and optimize an in-house method for host depletion and bacterial DNA extraction from positive blood cu...

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Literature Corpus work: 0199325b-ba66-583b-bac6-b4fba5f45d59
DOI: 10.64898/2026.07.20.739511

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