Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Next-generation diagnostics of bloodstream infections enabled by rapid whole-genome sequencing of bacterial cells purified from blood cultures

17 Mar 2025

Abstract excerpt

BACKGROUND: Blood culture (BC) remains the cornerstone for diagnosis of bloodstream infections (BSI), but the long turn-around time (TAT) hampers timely selection of appropriate chemotherapy. Novel molecular approaches have been developed to provide faster results but are also affected by limitations. We developed a analytical workflow named LC-WGS (Whole-Genome Sequencing of Liquid Colony) for rapid whole-genome...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacterial Identification and Susceptibility Testing
Share to Bacterial Infections and Vaccines
Share to Infective Endocarditis Diagnosis and Management

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 40101387
DOI: 10.1016/j.ebiom.2025.105633

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Next-generation diagnostics of bloodstream infections enabled by rapid whole-genome sequencing of bacterial cells purified from blood culturesPMID 40101387Read ↗

Comparative Evaluation of Sequencing Technologies for Detecting Antimicrobial Resistance in Bloodstream InfectionsSemantic proximity Read ↗

Rapid identification of microbial pathogens and antimicrobial resistance from bloodstream infections using long-read sequencingSemantic proximity Read ↗

From culture to clarity in four hours: accelerating clinical management of bloodstream infections using metagenomicsSemantic proximity Read ↗

Advances in Host Depletion and Pathogen Enrichment Methods for Rapid Sequencing–Based Diagnosis of Bloodstream InfectionSemantic proximity Read ↗

Bacterial genome sequencing in clinical microbiology: a pathogen-oriented reviewSemantic proximity Read ↗

Applying nanopore sequencing in the etiological diagnosis of bloodstream infectionSemantic proximity Read ↗

From Theory to Practice: Translating Whole-Genome Sequencing (WGS) into the Clinic.Semantic proximity Read ↗

An optimised method for bacterial nucleic acid extraction from positive blood culture broths for whole genome sequencing, resistance phenotype prediction and downstream molecular applicationsSemantic proximity Read ↗

Molecular Rapid Diagnostic Testing for Bloodstream Infections: Nanopore Targeted Sequencing with Pathogen-Specific PrimersSemantic proximity Read ↗

MultiSeq-AMR: A modular amplicon-sequencing workflow for rapid detection of bloodstream infection and antimicrobial resistance markersSemantic proximity Read ↗

Comprehensive detection of pathogens in immunocompromised children with bloodstream infections by next-generation sequencingSemantic proximity Read ↗

A new method using rapid Nanopore metagenomic cell-free DNA sequencing to diagnose bloodstream infections: a prospective observational studySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.