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PARiS: Probabilistic Assignment and Repartitioning of isomiR Sequences: A data-driven method for denoising isomiR read count data

2026-05-12

Abstract excerpt

MicroRNAs (miRNAs) are non-coding RNAs, approximately 18–24 nucleotides in length, with important gene regulatory functions. In small RNA sequencing (sRNA-seq), observed isoforms of miRNA, called isomiRs, arise from my biological and technical processes. Alterations in isomiR expression has been linked to a wide variety of human diseases, from cancers to neurological diseases. However, it is difficult to distingui...

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Literature Corpus work
45987a53-e254-560d-8f27-27545cedb873
DOI
10.64898/2026.05.09.723882
Open publication

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