Article
In Silico Analysis of Micro-RNA Sequencing Data.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2021
Aparicio-Puerta Ernesto, Fromm Bastian, Hackenberg Michael, Halushka Marc K
Abstract excerpt
High-throughput sequencing for micro-RNAs (miRNAs) to obtain expression estimates is a central method of molecular biology. Surprisingly, there are a number of different approaches to converting sequencing output into micro-RNA counts. Each has their own strengths and biases that impact on the final data that can be obtained from a sequencing run. This chapter serves to make the reader aware of the trade-offs one...
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