Article

Asbestos accelerates disease onset in a genetic model of Malignant Pleural Mesothelioma

2020-06-17

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Hypothesis</h4> Asbestos-driven inflammation contributes to malignant pleural mesothelioma beyond the acquisition of rate-limiting mutations. <h4>Methods</h4> Genetically modified conditional allelic mice that were previously shown to develop mesothelioma in the absence of exposure to asbestos were induced with lentiviral vector expressing Cre recombinase with and without intrapleural inje...

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Literature Corpus work: 45796bd0-e8a6-59b0-a1b4-03cbad47c6a4
DOI: 10.1101/2020.06.16.154815

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