Back to search

Article

Chronic Kidney Disease, Osteoporosis, and TNFRSF11A: Causal Insights and Therapeutic Implications Through Mendelian Randomization

2025-01-20

Abstract excerpt

<title>Abstract</title> <p>Purpose This study aims to evaluate the causal relationship between chronic kidney disease (CKD) and osteoporosis using two-sample Mendelian randomization (MR) and drug-target MR, and to investigate the potential association between TNFRSF11A and estimated glomerular filtration rate (eGFR). Methods The study utilized single nucleotide polymorphisms (SNPs) associated with eGFR and urin...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
455aece0-1da8-5975-98d0-8851e4f97741
DOI
10.21203/rs.3.rs-5825139/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Chronic Kidney Disease, Osteoporosis, and TNFRSF11A: Causal Insights and Therapeutic Implications Through Mendelian RandomizationDOI 10.21203/rs.3.rs-5825139/v1
Chronic kidney disease and osteoporosis: a two-sample Mendelian randomization studySemantic proximity
The Association between the Presence of Kidney Stones and the Risk of Developing Osteoporosis: A NHANES-based Cross-sectional Study and Mendelian Randomization AnalysisSemantic proximity
A practical guide for nephrologist peer reviewers: understanding and appraising Mendelian randomization studiesSemantic proximity
Osteoarthritis is a risk factor for renal function injury based on the National Health and Nutrition Examination Survey and Mendelian Randomized studySemantic proximity
Muscle-origin creatinine-cystatin C ratio is an osteoporosis marker in individuals with normal renal function: evidence from observational and Mendelian randomization analysis.Semantic proximity
The Protective Effect of Interleukin-1 Receptor Antagonist on Kidney Function: A Mendelian Randomization StudySemantic proximity
Mendelian randomization for nephrologistsSemantic proximity
Immune cell signatures and inflammatory mediators: unraveling their genetic impact on chronic kidney disease through Mendelian randomization.Semantic proximity
Mendelian Randomization Analysis as a Tool to Gain Insights into Causes of Diseases: A Primer.Semantic proximity
Causal Effect Between Total Cholesterol and Hdl Cholesterol as Risk Factors for Chronic Kidney Disease: A Mendelian Randomization StudySemantic proximity
Mendelian randomization uncovers a protective effect of interleukin-1 receptor antagonist on kidney functionSemantic proximity
Causal effects of systemic inflammatory regulators on chronic kidney diseases and renal function: a bidirectional Mendelian randomization studySemantic proximity
Select a neighboring publication to make it the new centre.