Article
Muscle-origin creatinine-cystatin C ratio is an osteoporosis marker in individuals with normal renal function: evidence from observational and Mendelian randomization analysis.
Frontiers in endocrinology - 1 Jan 2024
He Pei, Yang Yi-Qun, Wang Han, Zhang Ya-Qian, Gu Yu-Ni, Hong Chen-Cheng, Bo Lin, Deng Fei-Yan, Lei Shu-Feng
Abstract excerpt
Background: Creatinine-cystatin C ratio (CCR) has been demonstrated as an objective marker of sarcopenia in clinical conditions but has not been evaluated as an osteoporosis marker in individuals with normal renal function. Methods: We selected 271,831 participants with normal renal function from UK Biobank cohort. Multivariable linear/logistic regression and Cox proportional hazards model were used to...
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