Article

Functional ultrasound and brain connectivity reveal central nervous system compromise in Trembler-J mice, model of Charcot-Marie-Tooth disease

2024-08-05

Abstract excerpt

<title>Abstract</title> <p>The Charcot-Marie-Tooth-1E (CMT1E) disease is typically described as a peripheral neuropathy in humans, causing decreased nerve conduction, spastic paralysis, and tremor. The Trembler-J (TrJ) mice serve as a high fidelity model of this disease. Here, we use functional ultrasound (fUS) and functional connectivity (FC) to analyze TrJ mice’s brain activity during sensory stimulation and re...

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Literature Corpus work: 45537050-d839-5198-bc27-1bbf0e5b4217
DOI: 10.21203/rs.3.rs-4707786/v1

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Functional ultrasound and brain connectivity reveal central nervous system compromise in Trembler-J mice, model of Charcot-Marie-Tooth diseaseDOI 10.21203/rs.3.rs-4707786/v1Read

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