Article

What makes blood clots break off? A back-of-the-envelope computation to de-mystify blood clot embolization

2023-08-22

Abstract excerpt

One in four deaths worldwide is due to thromboembolic disease; that is, one in four people die from blood clots first forming and then breaking off or embolizing. Once broken off, clots travel downstream, where they occlude vital blood vessels such as those of the brain, heart, or lungs, leading to strokes, heart attacks, or pulmonary embolisms, respectively. Despite clots’ obvious importance, much remains to be u...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 452b2c11-a16a-563a-8a60-bfd636e2bb90
DOI: 10.21203/rs.3.rs-3253321/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

What makes blood clots break off? A back-of-the-envelope computation to de-mystify blood clot embolizationDOI 10.21203/rs.3.rs-3253321/v1Read

A Whole Blood Thrombus Mimic: Constitutive Behavior Under Simple ShearSemantic proximity Read

Blood clot fracture properties are dependent on red blood cell and fibrin contentSemantic proximity Read

Patient-specific "Physical Twin" artery-on-chip platform reveals complex flow-dependent VWF mechanobiology and guides personalized antithrombotic therapySemantic proximity Read

Investigating the two regimes of fibrin clot lysis: an experimental and computational approachSemantic proximity Read

Hemodynamic shear stress and its role in atherosclerosis.Semantic proximity Read

CFD-derived biomarkers in intermediate risk pulmonary embolism patients treated with mechanical thrombectomySemantic proximity Read

Microbubble-Induced Acoustic Softening in Human Blood: A Pilot Translational Study Toward Understanding Unexplained Sudden Cardiac CollapseSemantic proximity Read

[Biomechanic shear stress in carotid arteries and atherosclerosis development].Semantic proximity Read

The effect of factor VIII deficiencies and replacement and bypass therapies on thrombus formation under venous flow conditions in microfluidic and computational models.Semantic proximity Read

Uncertainty quantification of the lattice Boltzmann method focussing on studies of human-scale vascular blood flowSemantic proximity Read

Multi-physics simulations reveal hemodynamic impacts of patient-derived fibrosis-related changes in left atrial tissue mechanicsSemantic proximity Read

A Mechanogenetic Model of Exercise-Induced Pulmonary Haemorrhage in the Thoroughbred Horse.Semantic proximity Read