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Article

A Mechanogenetic Model of Exercise-Induced Pulmonary Haemorrhage in the Thoroughbred Horse.

Genes - 1 Nov 2019

Blott Sarah, Cunningham Hannah, Malkowski Laurène, Brown Alexandra, Rauch Cyril

Abstract excerpt

Exercise-induced pulmonary haemorrhage (EIPH) occurs in horses performing high-intensity athletic activity. The application of physics principles to derive a 'physical model', which is coherent with existing physiology and cell biology data, shows that critical parameters for capillary rupture are cell-cell adhesion and cell stiffness (cytoskeleton organisation). Specifically, length of fracture in the capillary...

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Source

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Identifiers

PMID: 31683933
DOI: 10.3390/genes10110880
PMCID: PMC6895809

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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