Article

Ultrastructural comparison of human kidney organoids and human fetal kidneys reveals features of hyperglycemic culture

2023-03-27

Abstract excerpt

Induced pluripotent stem cell (iPSC)–derived kidney organoids have the potential for a large variety of applications. However, they do not persist long in culture, for which reasons are still unclear. Furthermore, their morphological maturation, an essential feature for kidney function, has not been sufficiently assessed. Kidney organoids are transcriptionally much alike end-of-first-trimester fetal kidneys and pr...

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Literature Corpus work: 44cae19c-0ce0-5f58-9857-2664dc83b5f2
DOI: 10.1101/2023.03.27.534124

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