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Increased Uterine Androgen Receptor Protein Abundance Results in Implantation and Mitochondrial Defects in Pregnant Rats with Hyperandrogenism and Insulin Resistance

2021-03-01

Abstract excerpt

<title>Abstract</title> <p>In this study, we show that during normal rat pregnancy, there is a gestational stage-dependent decrease in androgen receptor (AR) abundance in the gravid uterus and that this is correlated with the differential expression of endometrial receptivity and decidualization genes during early and mid-gestation. In contrast, exposure to 5α-dihydrotestosterone (DHT) and insulin (INS) or DHT al...

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Literature Corpus work: 4451e4d4-42fd-569d-8c91-ddc8875024fc
DOI: 10.21203/rs.3.rs-251376/v1

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Increased Uterine Androgen Receptor Protein Abundance Results in Implantation and Mitochondrial Defects in Pregnant Rats with Hyperandrogenism and Insulin ResistanceDOI 10.21203/rs.3.rs-251376/v1Read

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