Article

Immunoglobulin profile and B-cell frequencies are altered with changes in the cellular micro-environment independent of the stimulation conditions

2019-10-24

Abstract excerpt

B-cells are essential in the defense against Mycobacterium tuberculosis . Studies on isolated cells may not accurately reflect the responses that occur in vivo due to the presence of other cells. This study elucidated the influence of microenvironment complexity on B-cell polarisation and function in the context of TB disease. B-cell function was tested in whole blood, PBMC’s and as isolated cells. The different...

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Literature Corpus work: 44453a4a-abab-549d-8ba4-46cb87629997
DOI: 10.1101/818153

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