Article

An antibody-drug conjugate targeting GPR56 demonstrates efficacy in preclinical models of colorectal cancer

2022-08-14

Abstract excerpt

Antibody-drug conjugates (ADCs) have become an increasingly successful class of anticancer therapy, particularly within the past few years. Though ADCs are in clinical trials for colorectal cancer (CRC), a candidate has yet to be approved. CRC continues to be a leading cause of cancer-related death, emphasizing the need to identify novel target antigens for ADC development. GPR56, a member of the 7TM receptor fami...

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Literature Corpus work: 44225ce6-cc33-59c3-ae8f-4f86de564d69
DOI: 10.1101/2022.08.11.503187

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