Article

Interrogating conserved elements of diseases using Boolean combinations of orthologous phenotypes

2015-04-13

Abstract excerpt

Conserved genetic programs often predate the homologous structures and phenotypes to which they give rise; eyes, for example, have evolved several dozen times, but their development seems to involve a common set of conserved genes. Recently, the concept of orthologous phenotypes (or phenologs) offered a quantitative way to describe this property. Phenologs are phenotypes or diseases from separate species who share...

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Literature Corpus work: 4413ac76-c9cf-5766-9665-0cbe5d883874
DOI: 10.1101/017947

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