The Monarch Initiative: an integrative data and analytic platform connecting phenotypes to genotypes across species.

doi:10.1093/nar/gkw1128

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Article

The Monarch Initiative: an integrative data and analytic platform connecting phenotypes to genotypes across species.

Nucleic acids research - 4 Jan 2017

Mungall Christopher J, McMurry Julie A, Köhler Sebastian, Balhoff James P, Borromeo Charles, Brush Matthew, Carbon Seth, Conlin Tom, Dunn Nathan, Engelstad Mark, Foster Erin, Gourdine J P, Jacobsen Julius O B, Keith Dan, Laraway Bryan, Lewis Suzanna E, NguyenXuan Jeremy, Shefchek Kent, Vasilevsky Nicole, Yuan Zhou, Washington Nicole, Hochheiser Harry, Groza Tudor, Smedley Damian, Robinson Peter N, Haendel Melissa A

Abstract excerpt

The correlation of phenotypic outcomes with genetic variation and environmental factors is a core pursuit in biology and biomedicine. Numerous challenges impede our progress: patient phenotypes may not match known diseases, candidate variants may be in genes that have not been characterized, model organisms may not recapitulate human or veterinary diseases, filling evolutionary gaps is difficult, and many...

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PMID: 27899636
DOI: 10.1093/nar/gkw1128
PMCID: PMC5210586

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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