Article
Prediction of gene-phenotype associations in humans, mice, and plants using phenologs.
BMC bioinformatics - 21 Jun 2013
Woods John O, Singh-Blom Ulf Martin, Laurent Jon M, McGary Kriston L, Marcotte Edward M
Abstract excerpt
BACKGROUND: Phenotypes and diseases may be related to seemingly dissimilar phenotypes in other species by means of the orthology of underlying genes. Such "orthologous phenotypes," or "phenologs," are examples of deep homology, and may be used to predict additional candidate disease genes. RESULT...
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