Article

Genome-Wide Association Study and Meta-Analysis of Phytosterols Identifies a Novel Locus for Serum Levels of Campesterol

2024-03-22

Abstract excerpt

<title>Abstract</title> <p>Sitosterolemia is a rare inherited disorder caused by mutations in the <italic>ABCG5</italic>/<italic>ABCG8</italic> genes. These genes encode proteins involved in the transport of plant sterols. Mutations in these genes lead to decreased excretion of phytosterols, which can accumulate in the body and lead to a variety of health problems, including premature coronary artery disease. We...

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Literature Corpus work: 440393d0-b4be-5690-b123-a1995132e700
DOI: 10.21203/rs.3.rs-4110050/v1

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