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Article

Dissecting the spermatogonial stem cell niche using spatial transcriptomics

1 Jul 2023

Abstract excerpt

Spermatogonial stem cells (SSCs) in the testis support the lifelong production of sperm. SSCs reside within specialized microenvironments called "niches," which are essential for SSC self-renewal and differentiation. However, our understanding of the molecular and cellular interactions between SSCs and niches remains incomplete. Here, we combine spatial transcriptomics, computational analyses, and functional...

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PMID: 37393620
DOI: 10.1016/j.celrep.2023.112737

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