Article

Reconstructed signaling and regulatory networks identify potential drugs for SARS-CoV-2 infection

2020-06-01

Abstract excerpt

Several molecular datasets have been recently compiled to characterize the activity of SARS-CoV-2 within human cells. Here we extend computational methods to integrate several different types of sequence, functional and interaction data to reconstruct networks and pathways activated by the virus in host cells. We identify key proteins in these networks and further intersect them with genes differentially expressed...

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Literature Corpus work: 43fa1528-9213-5a8f-a32e-4d5f13a435af
DOI: 10.1101/2020.06.01.127589

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