Article

A single-cell transcriptome atlas of adult male and female human hookworm <i>Ancylostoma ceylanicum</i>

2025-01-03

Abstract excerpt

<h4>Summary</h4> Hookworms infect over 500 million people globally and represent a major neglected tropical disease. The prevalence, high reinfection rate, limited drugs and emerging resistance underscore the need for new therapeutic or vaccine targets. To mitigate halted progress of discovering targets, we provide new molecular insights into sex-specific expression and cellular heterogeneity by generating the fi...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: ff325477-d092-5bee-a997-b68c72e666e8
DOI: 10.1101/2025.01.03.631133

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

A single-cell transcriptome atlas of adult male and female human hookworm <i>Ancylostoma ceylanicum</i>DOI 10.1101/2025.01.03.631133Read

Single-cell atlas of the first intra-mammalian developmental stage of the human parasite <i>Schistosoma mansoni</i>Semantic proximity Read

A single-cell atlas of the miracidium larva of the human blood fluke <i>Schistosoma mansoni</i> : cell types, developmental pathways and tissue architectureSemantic proximity Read

Chromosome-Contiguous Ancylostoma duodenale Reference Genome from a Single Archived Specimen Elucidates Human Hookworm Biology and Host–Parasite InteractionsSemantic proximity Read

Characterizing Ancylostoma caninum transcriptome and exploring nematode parasitic adaptation.Semantic proximity Read

The <i>in vivo</i> transcriptome of <i>Schistosoma mansoni</i> in two prominent vector species, <i>Biomphalaria pfeifferi</i> and <i>B. glabrata</i>Semantic proximity Read

The stage- and sex-specific transcriptome of the human parasite <i>Schistosoma mansoni</i>Semantic proximity Read

Hookworm genes encoding intestinal excreted-secreted proteins are transcriptionally upregulated in response to the host’s immune systemSemantic proximity Read

A single-cell atlas of <i>Plasmodium falciparum</i> transmission through the mosquitoSemantic proximity Read

Transcriptome of the parasitic flatworm <i>Schistosoma mansoni</i> during intra-mammalian developmentSemantic proximity Read

Single cell transcriptomics of the human parasite <i>Schistosoma mansoni</i> first intra-molluscan stage reveals tentative tegumental and stem cell regulatorsSemantic proximity Read

Spatial transcriptomics reveals antiparasitic targets associated with essential behaviors in the human parasite <i>Brugia malayi</i>Semantic proximity Read

Resolving the origins of secretory products and anthelmintic responses in a human parasitic nematode at single-cell resolutionSemantic proximity Read