Article
Floss-Mediated Gingival Mucosal Immunization with HBc-E18-3 VLPs Induces Long-Lasting Intestinal IgG and Provides a Candidate Strategy for Intervention of FcRn-Related Autoimmune Injury
2026-08-14
Abstract excerpt
Echovirus 18 (E18) is a predominant pathogen causing aseptic meningitis in children, and post-E18 infection frequently triggers myasthenia gravis-like autoimmune neurological damage. This pathological process relies on neonatal Fc receptor (FcRn)-mediated IgG transcytosis across mucosal barriers, and FcRn also acts as an essential functional receptor required for E18 attachment and uncoating during host cell invas...
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Identifiers and source
- Literature Corpus work
- 434dc62b-1b43-50cd-91ef-77d1d55f4ae7
- DOI
- 10.64898/2026.08.10.743934
