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Unraveling the potential of Giardia extracellular vesicles as a vaccine candidat

2024-03-14

Abstract excerpt

In this study, we investigated the role of Giardia EVs in cellular communication and their potential as vaccine candidates. Our findings revealed that Giardia EVs activate pro-inflammatory signalling cascades, including SAPK/JNK and ERK1/ERK2, as well as the NF-kB pathway, resulting in IκB-α degradation and p65 translocation to the nucleus, in mouse macrophages. Moreover, Giardia EVs increased the expression of ge...

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Literature Corpus work
213ecae8-980b-5df9-bbe6-9004182ca6c1
DOI
10.20944/preprints202403.0845.v1
Open publication

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Unraveling the potential of Giardia extracellular vesicles as a vaccine candidatDOI 10.20944/preprints202403.0845.v1
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