Article

Aging immune system-related blood cell DNA methylation can predict the onset of early stage colorectal cancer

2020-01-14

Abstract excerpt

<h4>Objective</h4> There is a body of evidence that the aging immune system is linked to cancer. Here, we hypothesized that ubiquitination might play a key gatekeeper role in immune system aging and tumorigenesis in CRC. Therefore, we will systematically study the DNA methylation of ubiquitination genes and screen candidate CRC marker that are correlated with both aging and immune cell compositions. <h4>Design</h...

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Literature Corpus work: 4300dbbb-c8a6-5bf7-b3a7-e8f485415dd4
DOI: 10.1101/2020.01.13.905299

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