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Ensemble-based virtual screening of <i>Mycobacterium tuberculosis</i> ClpC1 inhibitors

2021-07-06

Abstract excerpt

Tuberculosis (TB) is an airborne transmissible disease caused by Mycobacterium tuberculosis ( Mtb ), responsible for 1.3 million deaths per year. Due to increased cases of drug resistance to Mtb , a new treatment regime for TB needs to be discovered. ClpC1 plays a crucial role in the protein homeostasis of Mtb thus, presents as a promising target in controlling TB infection. The present study aimed to identify pot...

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Literature Corpus work
42fda83f-678b-5086-b69e-30f49e1201c5
DOI
10.3762/bxiv.2021.50.v1
Open publication

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