Article

Extracellular vesicles from diverse fungal pathogens induce species-specific and endocytosis-dependent immunomodulation

2025-01-03

Abstract excerpt

<h4>ABSTRACT</h4> Microbial pathogens generate extracellular vesicles (EVs) for intercellular communication and quorum sensing. Microbial EVs also induce inflammatory pathways within host innate immune cells. We previously demonstrated that EVs secreted by Candida albicans trigger type I interferon signaling in host cells specifically via the cGAS-STING innate immune signaling pathway. Here, we show that despite...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 42f460ae-359a-56ed-8fdb-ef396928780b
DOI: 10.1101/2025.01.03.631181

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Extracellular vesicles from diverse fungal pathogens induce species-specific and endocytosis-dependent immunomodulationDOI 10.1101/2025.01.03.631181Read

Cross-Species Communication via Fungal Extracellular VesiclesSemantic proximity Read

Comparative molecular and immunoregulatory analysis of extracellular vesicles from <i>Candida albicans</i> and <i>Candida auris</i>Semantic proximity Read

Fungal extracellular vesicle-mediated regulation: from virulence factor to clinical applicationSemantic proximity Read

Fungal extracellular vesicles are involved in intraspecies intracellular communicationSemantic proximity Read

Extracellular vesicles produced during fungal infection in humans are immunologically activeSemantic proximity Read

Fungal Extracellular Vesicles as Potential Targets for Immune InterventionsSemantic proximity Read

Comparative Molecular and Immunoregulatory Analysis of Extracellular Vesicles from Candida albicans and Candida aurisSemantic proximity Read

Characteristics and potential clinical applications of the extracellular vesicles of human pathogenic FungiSemantic proximity Read

Structure, composition and biological properties of fungal extracellular vesiclesSemantic proximity Read

Mechanisms of fungal pathogenic DNA-activated STING pathway in biofilms and its implication in dental caries onsetSemantic proximity Read

Small extracellular vesicles secreted by Candida albicans hyphae have highly diverse protein cargoes that include virulence factors and stimulate macrophagesSemantic proximity Read

Lipid Flippase Mediated Membrane Asymmetry Governs Extracellular Vesicles Biogenesis and Host Interactions in <i>Cryptococcus neoformans</i>Semantic proximity Read