Article

IMIX: A multivariate mixture model approach to integrative analysis of multiple types of omics data

2020-06-24

Abstract excerpt

<h4>Motivation</h4> Integrative genomic analysis is a powerful tool to study the biological mechanisms underlying a complex disease or trait across multiplatform high-dimensional data, such as DNA methylation, copy number variation (CNV), and gene expression. It is common to perform large-scale genome-wide association analysis of an outcome for each data type separately and combine the results ad hoc , leading t...

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Literature Corpus work: 42dadd5e-9e59-5d46-ac78-a00a3ba742b1
DOI: 10.1101/2020.06.23.167312

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