Article

Mutual information for detecting multi-class biomarkers when integrating multiple bulk or single-cell transcriptomic studies

2024-06-13

Abstract excerpt

<h4>Motivation</h4> Biomarker detection plays a pivotal role in biomedical research. Integrating omics studies from multiple cohorts can enhance statistical power, accuracy and robustness of the detection results. However, existing methods for horizontally combining omics studies are mostly designed for two-class scenarios (e.g., cases versus controls) and are not directly applicable for studies with multi-class...

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Literature Corpus work: e39d1323-5fc7-56ec-8f54-db4e44e7594b
DOI: 10.1101/2024.06.11.598484

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