Article

Alphaviral capsid proteins inhibit stress granule assembly via competitive RNA binding with G3BP1

2025-12-02

Abstract excerpt

Viral infection is one of the conditions that induces stress granule (SG) formation, a cellular defense mechanism that exerts antiviral effects. To counteract this host response, viruses have evolved a broad spectrum of strategies to inhibit SG formation. However, the molecular mechanisms underlying SG inhibition remain poorly understood. The nucleocapsid proteins play a critical role in virus replication and host...

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Literature Corpus work: 42b58971-bd76-5dbc-b9f2-6a13215d3d22
DOI: 10.64898/2025.12.01.691496

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