Article

Kidins220 sets the threshold for survival of neural stem cells and progenitors to sustain adult neurogenesis

2023-01-10

Abstract excerpt

<h4>ABSTRACT</h4> In the adult mammalian brain, neural stem cells (NSCs) located in highly restricted niches sustain the generation of new neurons that integrate into existing circuits. A reduction in adult neurogenesis is linked to ageing and neurodegeneration, whereas dysregulation of proliferation and survival of NSCs have been hypothesized to be at the origin of glioma. Thus, unravelling the molecular underpi...

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Literature Corpus work: 42596d01-95ac-5327-80cc-95988d7b730c
DOI: 10.1101/2023.01.10.523252

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