Article
Mining the <b><i>Leishmania</i></b> genome for novel antigens and vaccine candidates
10 Feb 2009
Abstract excerpt
Leishmaniasis is a neglected disease with an estimated 12 million infected people. The recent completion of the sequencing of the Leishmania major genome has opened opportunities for the identification of targets for vaccine development. We present here the first attempt at identifying novel vaccine candidates by whole genome analysis. We predicted CD8(+) T cell epitopes from the L. major proteome and validated...
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