Article

Estimating Assembly Base Errors Using K-mer Abundance Difference (KAD) Between Short Reads and Genome Assembled Sequences

2020-03-18

Abstract excerpt

<h4>ABSTRACT</h4> Genome sequences provide genomic maps with a single-base resolution for exploring genetic contents. Sequencing technologies, particularly long reads, have revolutionized genome assemblies for producing highly continuous genome sequences. However, current long-read sequencing technologies generate inaccurate reads that contain many errors. Some errors are retained in assembled sequences, which ar...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 41f96359-3cd3-5145-b3dc-755ac2489c75
DOI: 10.1101/2020.03.17.994566

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Estimating Assembly Base Errors Using K-mer Abundance Difference (KAD) Between Short Reads and Genome Assembled SequencesDOI 10.1101/2020.03.17.994566Read

Recent advances in sequence assembly: principles and applications.Semantic proximity Read

A hybrid and scalable error correction algorithm for indel and substitution errors of long reads.Semantic proximity Read

Merqury: reference-free quality, completeness, and phasing assessment for genome assembliesSemantic proximity Read

Towards complete and error-free genome assemblies of all vertebrate speciesSemantic proximity Read

Measuring DNA contents of animal and plant genomes with Gnodes, the long and short of itSemantic proximity Read

Comprehensive Survey and Guidance for Building High Quality Genome AssemblySemantic proximity Read

Implications of error-prone long-read whole-genome shotgun sequencing on characterizing reference microbiomesSemantic proximity Read

Genome assembly quality: assessment and improvement using the neutral indel model.Semantic proximity Read

Salvaging complete and high-quality genomes of novel microbial species from a meromictic lake using a workflow combining long- and short-read sequencing platformsSemantic proximity Read

Genome sequencing and assembly.Semantic proximity Read

Evaluation of the accuracy of bacterial genome reconstruction with Oxford Nanopore R10.4.1 long-read-only sequencingSemantic proximity Read

PG-SCUnK: measuring pangenome graph representativeness using single-copy and universal K-mers.Semantic proximity Read