Article

Manganese-doped nanowires protect Tregs from endothelial peroxynitrite in periodontitis

2026-06-01

Abstract excerpt

<title>Abstract</title> <p> Periodontitis is a prevalent inflammatory disease that causes progressive alveolar bone loss, which is exacerbated by dysregulation of regulatory T (Treg) cells. Endothelial injury has emerged as an important regulator of periodontal immunity, but how injured endothelial cells reshape local Treg-associated adaptive immunity remains insufficiently defined. We integrated public single-c...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 41f52d0f-5823-5fdc-826c-a0f142551b1e
DOI: 10.21203/rs.3.rs-9790381/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Manganese-doped nanowires protect Tregs from endothelial peroxynitrite in periodontitisDOI 10.21203/rs.3.rs-9790381/v1Read

CD38⁺ Endothelial Remodeling Defines Spatially Diverse Vasculopathy Programs in Rapidly Advancing Oral InflammationSemantic proximity Read

Cationic Nanostructures for the Treatment of Inflammatory Bone LossSemantic proximity Read

Periodontal Disease, Chronic Silent Inflammation, and Micro/Nanoplastics: An Environmental Microbiology Review of Oral Biofilm Retention, Dysbiosis, and Systemic Risk PathwaysSemantic proximity Read

Gli1+ Inflamm-Stem Cells Engage Extracellular Vesicles to Prime Aberrant Neutrophils for Exacerbating Periodontal ImmunopathologySemantic proximity Read

Nanozymes for Non-neoplastic Diseases: Catalytic Therapy RedefinedSemantic proximity Read

Th17/Treg balance and indoleamine 2,3 dioxygenase activity in periodontitis-associated atherosclerotic patientsSemantic proximity Read

Inflammasome Modulation Enhances the Immunoregulatory Function of Mesenchymal Stromal Cells under Bacterial and Titanium-induced InflammationSemantic proximity Read

Human Bone Marrow Mesenchymal Stem Cell-derived Extracellular Vesicles Restore Th17/Treg Homeostasis in Periodontitis via miR-1246Semantic proximity Read

RNA-seq of THP-1 and U937 exposed to enamel matrix derivativeSemantic proximity Read

NETs Are Double-Edged Swords with the Potential to Aggravate or Resolve Periodontal Inflammation.Semantic proximity Read

Glipizide alleviates periodontitis pathogenicity via inhibition of angiogenesis, osteoclastogenesis, and M1/M2 macrophage ratio in periodontal tissueSemantic proximity Read

Effects of Porphyromonas gingivalis lipopolysaccharide on the behavior of human dental pulp stem cells in vitro and their inflammation-related transcriptomics profileSemantic proximity Read