Article

Glipizide alleviates periodontitis pathogenicity via inhibition of angiogenesis, osteoclastogenesis, and M1/M2 macrophage ratio in periodontal tissue

2023-03-24

Abstract excerpt

New consensus indicates type 2 diabetes mellitus (T2DM) and periodontitis as comorbidity and may share common pathways of disease progression. Sulfonylureas have been reported to improve the periodontal status in periodontitis patients. Glipizide, a sulfonylurea widely used in the treatment of T2DM, has also been reported to inhibit inflammation and angiogenesis. However, the effect of Glipizide on periodontitis p...

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Literature Corpus work: 53b57479-70a9-587b-b119-32717fea63da
DOI: 10.21203/rs.3.rs-2705322/v1

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