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Article

NETs Are Double-Edged Swords with the Potential to Aggravate or Resolve Periodontal Inflammation.

Cells - 5 Dec 2020

Vitkov Ljubomir, Minnich Bernd, Knopf Jasmin, Schauer Christine, Hannig Matthias, Herrmann Martin

Abstract excerpt

Periodontitis is a general term for diseases characterised by inflammatory destruction of tooth-supporting tissues, gradual destruction of the marginal periodontal ligament and resorption of alveolar bone. Early-onset periodontitis is due to disturbed neutrophil extracellular trap (NET) formation and clearance. Indeed, mutations that inactivate the cysteine proteases cathepsin C result in the massive periodontal...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33291407
DOI: 10.3390/cells9122614
PMCID: PMC7762037

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