Article

Identification of druggable host dependency factors shared by multiple SARS-CoV-2 variants of concern

2023-01-09

Abstract excerpt

The high mutation rate of SARS-CoV-2 leads to emergence of several variants, some of which are resistant to vaccines and drugs targeting viral elements. Targeting host dependency factors – cell proteins required for viral replication - would help avoid resistance. However, whether different SARS-CoV-2 variants induce conserved cell responses and exploit the same core host factors is still unclear. We compared thre...

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Literature Corpus work: 41d9538e-4384-5b16-aad3-adab03640191
DOI: 10.1101/2023.01.09.523209

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