Article

Development of a cross-protective common cold coronavirus vaccine

2025-05-14

Abstract excerpt

Common cold coronaviruses, such as OC43 and HKU1, generally cause mild respiratory infections in healthy people. However, they can lead to severe illness in high-risk groups, including immunocompromised individuals and older adults. Currently, there is no clinically approved vaccine to prevent infection by common cold coronaviruses. Here, we developed an mRNA vaccine expressing a stabilized spike protein derived f...

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Literature Corpus work: 4182beaa-0fc7-538e-8ed2-310a42225427
DOI: 10.1101/2025.05.12.653567

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