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SARS-CoV-2 B.1.1.7 and B.1.351 Spike variants bind human ACE2 with increased affinity

2021-02-22

Abstract excerpt

SARS-CoV2 being highly infectious has been particularly effective in causing widespread infection globally and more variants of SARS-CoV2 are constantly being reported with increased genomic surveillance. In particular, the focus is on mutations of Spike protein, which binds human ACE2 protein enabling SARS-CoV2 entry and infection. Here we present a rapid experimental method leveraging the speed and flexibility o...

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Literature Corpus work
415d1fae-8242-5ee8-8ac3-5b4386cd1d2f
DOI
10.1101/2021.02.22.432359
Open publication

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SARS-CoV-2 B.1.1.7 and B.1.351 Spike variants bind human ACE2 with increased affinityDOI 10.1101/2021.02.22.432359
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