Article

Multi-Omics Profiling Identifies Biomarker Candidates and Pathogenic Divergence Between Post-Transplant Diabetes Mellitus and Type 2 Diabetes

2025-10-10

Abstract excerpt

<title>Abstract</title> <p>Background Post-transplant diabetes mellitus (PTDM) is a significant complication following liver transplantation, primarily induced by immunosuppressive agents like tacrolimus. While PTDM shares some clinical features with type 2 diabetes (T2D), its distinct pathogenesis remains poorly understood. Methods We developed mouse models of PTDM and T2D using tacrolimus, streptozotocin (STZ),...

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Literature Corpus work: 4104a7b2-d2d8-5333-ab14-19269ac714b7
DOI: 10.21203/rs.3.rs-7682951/v1

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