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Article

Cigarette smoke induces miR-132 in Th17 cells that enhance osteoclastogenesis in inflammatory arthritis

23 Dec 2020

Abstract excerpt

Significance This report reveals a mechanism by which cigarette smoke (CS) could exacerbate local inflammatory disease. CS is a key environmental pollutant affecting millions of people globally and continues to be of considerable interest to the biomedical communities. We found that CS activates the AhR on Th17 cells, leading to the up-regulation of miR-132 , which is then packaged into extracellular vesicles...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 33443169
DOI: 10.1073/pnas.2017120118

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