Article

Serotonin sensing by microglia conditions the proper development of neuronal circuits and of social and adaptive skills

2022-03-10

Abstract excerpt

The proper maturation of emotional and sensory circuits requires a fine tuning of serotonin (5-HT) level during early postnatal development. Consistently, dysfunctions of the serotonergic system have been associated with neurodevelopmental psychiatric diseases, including autism spectrum disorders (ASD). However, the mechanisms underlying the developmental effects of 5-HT remain partially unknown, one obstacle bein...

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Literature Corpus work: 40b89ec3-f6de-5848-8bd4-dda003300515
DOI: 10.1101/2022.03.09.483609

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