Article

Inhibition of the lncRNA 585189 prevents podocyte injury and mitochondria dysfunction by promoting hnRNP A1 and SIRT1 in diabetic nephropathy

2022-11-08

Abstract excerpt

Podocyte damage is a crucial cause for diabetic nephropathy and end-stage renal disease. Moreover, mitochondria play an indispensable role in diabetic nephropathy and high glucose-associated podocyte damage. Through RNA sequencing, we firstly discovered that long non-coding RNA (lncRNA) ENST00000585189.1 (lncRNA 585189), was up-regulated in the plasma of patients diagnosed with DN, accompanied with higher albumin/...

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Literature Corpus work: 40af9e5a-5331-5002-8ab2-bb0ed4a0585c
DOI: 10.21203/rs.3.rs-2229530/v1

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