Article
LINC00162 participates in the pathogenesis of diabetic nephropathy via modulating the miR-383/HDAC9 signalling pathway.
Artificial cells, nanomedicine, and biotechnology - 1 Dec 2020
Fan WenXing, Wen XiaoLing, Zheng JinFeng, Wang KunHua, Qiu HongYu, Zhang Jing, Su Feng
Abstract excerpt
Diabetic nephropathy (DN) is a common chronic complication of diabetes. In this study, we aimed to explore the potential role of lncRNA LINC-00162 in the pathogenic process of DN. LncRNA microarray analysis, real-time PCR, IHC computational analysis and luciferase assay were performed to explore the regulatory relationship among LINC00162, miR-383 and HDAC9. There was an obvious difference between T2D + DN and...
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