Article
Simultaneous adjunctive treatment of malaria and its co-evolved genetic disorder sickle cell anaemia
2022-09-02
Abstract excerpt
Effective treatments for genetic disorders that co-evolved with pathogens require simultaneous betterment of both conditions. Hydroxyurea (HU) offers safe and efficacious treatment for sickle cell anemia (SCA) by reducing clinical complications, transfusions, and death. Despite concerns that HU-treatment for SCA would increase infection risk by the human malaria Plasmodium falciparum , (the genetic driver of the...
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Identifiers and source
- Literature Corpus work
- 40a8b686-9766-584d-a10c-72a8ee85c5a9
- DOI
- 10.1101/2022.09.01.506230