Article

Structural and functional characterisation of adhesin and effector proteins from pathogenic fungi

2016-01-01

Abstract excerpt

This PhD has focussed on characterising two proteins key to fungal infections; the Als adhesins and BEC1054. The Als (agglutinin-like sequence) family of surface adhesins are critical virulence factors from Candida albicans, contributing to biofilm formation and colonisation of a range of tissues in the human host. The broad tissue tropism of Als has been linked to a broadly specific peptide binding cavity (pbc) i...

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Literature Corpus work: 40a5ec4f-20a0-55e8-a05e-5b20fd14422c
DOI: 10.25560/58140

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