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Candida albicans Als3, a Multifunctional Adhesin and Invasin

30 Nov 2010

Abstract excerpt

Candida albicans is part of the normal human flora, and it grows on mucosal surfaces in healthy individuals. In susceptible hosts, this organism can cause both mucosal and hematogenously disseminated disease. For C. albicans to persist in the host and induce disease, it must be able to adhere to biotic and abiotic surfaces, invade host cells, and obtain iron. The C. albicans hypha-specific surface protein Als3 is...

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PMID: 21115738
DOI: 10.1128/ec.00279-10

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