Article
Dynamic Optimization with Particle Swarms (DOPS): A meta-heuristic for parameter estimation in biochemical models
2017-12-28
Abstract excerpt
<h4>Background</h4> Mathematical modeling is a powerful tool to analyze, and ultimately design biochemical networks. However, the estimation of the parameters that appear in biochemical models is a significant challenge. Parameter estimation typically involves expensive function evaluations and noisy data, making it difficult to quickly obtain optimal solutions. Further, biochemical models often have many local e...
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Identifiers and source
- Literature Corpus work
- 3fe945dc-caf6-531e-887a-76fc9c273ca0
- DOI
- 10.1101/240580