Article
Retroviral Replicating Vector Toca 511 (<i>vocimagene amiretrorepvec</i>) for Prodrug Activator Gene Therapy of Lung Cancer
2022-07-01
Abstract excerpt
Therapeutic efficacy of retroviral replicating vector (RRV)-mediated prodrug activator gene therapy has been demonstrated in a variety of tumor models, but clinical investigation of this approach has so far been restricted to glioma and gastrointestinal malignancies. In the present study, we evaluated replication kinetics, transduction efficiency, and therapeutic efficacy of RRV in experimental models of lung canc...
Identifiers and source
- Literature Corpus work
- 3f97db38-01c6-5fc6-a2e2-0cb231e65d2b
- DOI
- 10.20944/preprints202207.0015.v1
